研究業績

2018年

論文

 研究室

  1. Tokinoya Katsuyuki, Shiromoto Jun, Sugasawa Takehito, Yoshida Yasuko, Aoki Kai, Nakagawa Yoshimi, Ohmori Hajime, Takekoshi Kazuhiro: Influence of acute exercise on renalase and its regulatory mechanism. Life Sciences, in press 2018.

 

共同研究(著者)

  1. Tanaka K, Sasai H, Wakaba K, Murakami S, Ueda M, Yamagata F, Sawada M, Takekoshi K: Professional dietary coaching within a group chat using a smartphone application for weight loss: a randomized controlled trial. J Multidiscip Healthc,11:339-347, 2018. 
  2. Tagawa K, Ra SG, Kumagai H, Yoshikawa T, Yoshida Y, Takekoshi K, Sakai S, Miyauchi T, Maeda S: Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men. Physiol Res, 67(Supplementum 1):S155-S166, 2018.
  3. Naruse M, Satoh F, Tanabe A, Okamoto T, Ichihara A, Tsuiki M, Katabami T, Nomura M, Tanaka T, Matsuda T, Imai T, Yamada M, Harada T, Kawata N, Takekoshi K: Efficacy and safety of metyrosine in pheochromocytoma/paraganglioma: a multi-center trial in Japan. Endocr J, 65(3):359-37, 2018.

2017年

論文

研究室

  1. Yasuko Yoshida, Takehito Sugasawa, Katsuyuki Tokinoya, Namba Shunji, Kazuhiro Takekoshi: Epinephrine upregulates renalase expression in cultured C2C12 muscle cells, International Journal of Analytical Bio-Science, 5(4): 61-65. 2017.
  2. Yasuko Yoshida, Takehito Sugasawa, Masaya Hoshino, Katsuyuki Tokinoya, Keisuke Ishikuram, Hajime Ohmori, Kazuhiro Takekoshi: Transient changes in serum renalase concentration during long-distance running: The case of an amateur runner under continuous training, The Japanese Society of Physical Fitness and Sports Medicine, 6(3): 159-166. 2017.
  3. Takehito Sugasawa, Yasuko Yoshida, Katsuyuki Tokinoya, Kazuhiro Takekoshi: Conservative Treatment with Continuous Cryotherapy as a Japanese Judo Therapy for Jones Fracture: A Case Report, Journal of Trauma & Treatment, 6(4): 2017.

 

共同研究(著者)

  1. Shibata M, Inaishi T, Miyajima N, Adachi Y, Takano Y, Nakanishi K, Takeuchi D, Noda S, Aita Y, Takekoshi K, Kodera Y, Kikumori T: Synchronous bilateral pheochromocytomas and paraganglioma with novel germline mutation in MAX: a case report. Surg Case Rep, 28;3(1):131, 2017.
  2. Matsumura-Matsuda E, Sekiya M, Omoto-Inuzuka M, Santo K, Shikama A, Kuba M, Sugano Y, Iwasaki H, Yatoh S, Sato T, Hara H, Takekoshi K, Suzuki H, Shimano H: A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges. Intern Med, 57(7):979-985, Epub 2017.
  3. Saitoh K, Yonemoto T, Usui T, Takekoshi K, Suzuki M, Nakashima Y, Yoshimura K, Kosugi R, Ogawa T, Inoue T: Novel germline variant of TMEM127 gene in a patient with familial pheochromocytoma. Endocrinol Diabetes Metab Case Rep, 2017.
  4. Misu H, Takayama H, Saito Y, Mita Y, Kikuchi A, Ishii KA, Chikamoto K, Kanamori T, Tajima N, Lan F, Takeshita Y, Honda M, Tanaka M, Kato S, Matsuyama N, Yoshioka Y, Iwayama K, Tokuyama K, Akazawa N, Maeda S, Takekoshi K, Matsugo S, Noguchi N, Kaneko S, Takamura T: Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle. Nat Med, 23(4):508-516, 2017.

2016年

論文

  1. Takehito Sugasawa, Naoki Mukai, Satoru Oshiro, Takafumi Handa, Ikumi Tanabe, Yuko Kumaki, Kyoko Tamura, Taiko Tanba, Norihiko Moriyama, Kazuhiro Takekoshi: The effects of cold stimulations of various temperatures on cell growth and metabolic activity of human cells in vitro, GAZZETTA MEDICA ITALIANA, 175(1-2): 15-22. 2016.
  2. Takehito Sugasawa, Naoki Mukai, Kyoko Tamura, Taiko Tamba, Shintaro Mori, Yuki Miyashiro, Mami Yamaguchi, Norihiko Moriyama, Sumiko Nissato, Song-Gyu Ra, Yasuko Yoshida, Yasushi Kawakami, Kazuhiro Takekoshi. Effects of cold stimulation on mitochondrial activity and VEGF expression in vitro. Int J Sports Med. DOI: 10.1055/s-0042-102659.
  3. 菅澤威仁, 向井直樹, 丹波泰子, 竹越一博・他: 異なる温度の冷却刺激が細胞のカタラーゼ活性に及ぼす影響, 理療, Vol .46, No. 1, 2016.
  4. Takehito Sugasawa, Naoki Mukai, Kyoko Tamura, Kazuhiro Takekoshi et al. : Effect of closed fracture on spot urinary thiobarbituric acid reactive substance level in old rats. GAZZETTA MEDICA ITALIANA, 2016 (in press). 

2015年

論文

  1. 菅澤威仁, 井上知, 大塚絢香, 向井直樹, 丹波泰子, 竹越一博: マッサージ療法のエビデンス, 理療, Vol.44, No.4, pp72-81, 2015.
  2. 菅澤威仁, 向井直樹, 丹波泰子, 田村京子, 森山紀彦, 竹越一博: 異なる温度の冷却刺激が細胞の代謝活性および増殖に及ぼす影響 -Rat Pheochromocytoma cellを用いた検討-, 理療, Vol.45, No.1, pp76-81, 2015. 
  3. Youngju Choi, Masahiro Miura, Yoshio Nakata, Takehito Sugasawa, Sumiko Nissato, Takeshi Otsuki, Jun Sugawara, Yasushi Kawakami, Hitoshi Shimano, Yoshimi Iijima, Kiyoji Tanaka, Shinya Kuno, Nitish R. Mahapatra, Seiji Maeda, Kazuhiro Takekoshi. A common genetic variant of the chromogranin a-derived peptide catestatin is associated with atherogenesis and hypertension in a Japanese population. Endocrine Journal. doi: 10.1507/endocrj. EJ15-0471. 2015.
  4. Saito Y, Ishii KA, Aita Y, Ikeda T, Kawakami Y, Shimano H, Hara H, Takekoshi K . Loss of SDHB Elevates Catecholamine Synthesis and Secretion Depending on ROS Production and HIF Stabilization. Neurochem Res. 2016 Apr;41(4):696-706. doi: 10.1007/s11064-015-1738-3. Epub 2015 Nov 30.

2014年

論文

  1. Tanaka Y, Isobe K, Enbo Ma, Imai T, Kikumori T, Matsuda T, Maeda Y, Sakurai A, Midorikawa S, Hataya Y, Kato T, Kamide K, Ikeda Y, Okada Y, Adachi M, Yanase T, Takahashi H, Yokoyama C, Arai Y, Hashimoto K, Shimano H, Hara H, Kawakami Y, Takekoshi K: Plasma Free Metanephrines in the Diagnosis of Pheochromocytoma: DiagnosticAccuracy and Strategies for Japanese Patients. Endocr J, 2014.

2013年

論文

  1. Ikeda T, Ishii KA, Saito Y, Miura M, Otagiri A, Kawakami Y, Shimano H, Hara H, Takekoshi K: Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells. J Pharmacol Sci, Vol.121,67-73, 2013.

2012年

論文

  1. Saito Y, Tanaka Y, Aita Y, Ishii KA, Ikeda T, Isobe K, Kawakami Y, Shimano H, Hara H, Takekoshi K: Sunitinib induces Apoptosis in Pheochromocytoma Tumor Cells by Inhibiting VEGFR2/AKT/mTOR/S6K1 Pathways Through Modulation of Bcl-2 and BAD. Am J Physiol Endocrinol Metab, vol.302, E615-625, 2012
  2. Aita Y, shii KA, Ishii KA, Saito Y, Ikeda T, Kawakami Y, Shimano H, Takekoshi K:.Sunitinib Inhibits Catecholamine Synthesis and Secretion in Pheochromocytoma Tumor Cells by Blocking VEGF Receptor 2 via PLC-γ-related Pathways. Am J Physiol Endocrinol Metab, vol.303, E1006-14, 2012.
  3. Takeichi N, Midorikawa S, Watanabe A, Naing BT, Tamura H, Kano T, Sugihara T, Nissato S, Saito Y, Aita Y, Ishii K, Igarashi T, Kawakami Y, Hara H, Ikeda T, Shimizu T, Suzuki S, Shimano H, Kawamoto M, Shimada T, Watanabe T, Oikawa S, Takekoshi K:Identical germline mutations in the TMEM127 gene in 2 unrelated Japanese patients with bilateral pheochromocytoma. Clin Endocrinol, vol.77, 707-14. 2012.

学会発表

  1. Tokinoya, K., Shiromoto, J., Sugasawa, T., Yoshida, Y., Ohmori, H., Takekoshi, K:Influence on renalase by acute exercise and its regulatory mechanism. The 23th European College of Sport Science, Ireland(Dublin). 2018. 7.
  2. 時野谷勝幸, 吉田保子, 菅澤威仁, 森田将平, 竹越一博:タウリン添加による代謝制御に関するマイオカインの応答.第4回国際タウリン研究会 日本部会,熊本,2018.3.
  3. Katsuyuki Tokinoya, Yasuko Yoshida, Takehito Sugasawa, Yuichi Aita, Jun Shiromoto, Kai Aoki, Hajime Ohmori, Kazuhiro Takekoshi : Renalase might regulate catecholamine by skeletal muscle during exercise. The 22ndShizuoka Forum on Health and Longevity, Shizuoka, 2017. 11.
  4. 時野谷 勝幸,吉田 保子,菅澤 威仁,星野 雅也,石倉 惠介,大森 肇,竹越 一博:一過性の長距離走中における血中レナラーゼ濃度の変化. 第72回日本体力医学会大会,和歌山,2017.9.
  5. 吉田 保子,菅澤 威仁,時野谷 勝幸,星野 雅也,難波 俊二,竹越 一博:筋細胞(L6 cell)における renalase 発現の検討. 第66回 日本医学検査学会,千葉,2017.6.
  6. 菅澤威仁, 向井直樹, 丹波泰子, 田村京子, 吉田保子, 竹越一博: 異なる温度の冷却刺激が細胞のPGC1-αの発現に及ぼす影響 -フローサイトメトリーを用いた検討-,第65回日本理学療法学会, 静岡県清水市, 平成28年5月.
  7. Takehito Sugasawa, Naoki Mukai, Kyoko Tamura, Taiko Tamba, Kazuhiro Takekoshi: The effects of cold stimulations of various temperatures on mitochondrial functions and biogenesis and expression of vascular endothelial growth factor (VEGF) of human cells in vitro, 第24回日本柔道整復接骨医学会学術大会, 新潟県新潟市, 平成27年11月.
  8. Takehito Sugasawa, Taiko Tanba, Kyoko Tamura, Kazuhiro Takekoshi: The influence of fracture on the urinary thiobarbituric acid reactive substance (TBARS) in rats, 第23回日本柔道整復接骨医学会学術大会, 東京都大田区, 平成26年11月.
  9. Takehito Sugasawa, Kazuhiro Takekoshi, Taiko Tanba, Kyoko Tamura, Takafumi Handa, Yuko Kumaki, Norihiko Moriyama, Naoki Mukai: The effects of cold stimulations of various temperatures on cell growth and metabolism activity for human cultured cells, 第87回日本生化学会大会, 京都府京都市, 平成26年10月. 
  10. 菅澤威仁, 大城聰: ヒト培養細胞における異なる温度刺激が代謝活性に及ぼす影響 ─温熱療法および寒冷療法の検討─,第22回日本柔道整復接骨医学会学術大会, 東京都江東区, 平成25年11月.
  11. Takehito Sugasawa, Taiko Tanba, Yuya Iwasawa, Takumi Sibuya, Kin-ya Hayakawa, Satoru Oshiro: Icing suppresses tissue damages and oxidative stress in a rat fracture rat model, 第21回日本柔道整復接骨医学会学術大会, 福岡県福岡市, 平成24年11月.
  12. 菅澤威仁, 向井直樹, 丹波泰子, 田村京子, 竹越一博: 異なる温度の冷却刺激が細胞の抗酸化能に及ぼす影響-ヒト線維芽細胞を用いた検討-, 第64会日本理学療法学会, 愛媛県松山市, 平成27年5月.
  13. 菅澤威仁, 竹越一博、向井直樹: 異なる冷却刺激が細胞の代謝活性および増殖に及ぼす影響 –ラット褐色細胞腫脂肪 (PC12 cell)を用いた検討, 関東甲信越理学療法学会, 長野県佐久平市, 2014年11月.

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